Immediately After the Procedure
You wake up in a recovery room and stay there for several hours while your recovery from anesthesia is monitored, after which you are taken to a hospital room or discharged home (American Academy of Orthopaedic Surgeons/OrthoInfo, November 2023). Knee replacement is usually done under general anesthesia or under spinal/regional anesthesia combined with moderate (conscious) sedation, and which one you had changes how quickly you feel clear-headed.
In those first hours, staff check your blood pressure, pulse, breathing and oxygen level, look at the dressing on your knee, and check the circulation, feeling and movement in your foot and ankle. You will be asked to rate your pain, and a nurse or physical therapist will usually get you standing or taking a few steps with a walker on the day of surgery or the morning after. Pain control often combines acetaminophen (Tylenol) with a short course of an opioid such as oxycodone (OxyContin, also found in Percocet), plus a clot-prevention medicine such as enoxaparin (Lovenox) or aspirin — which medicines, how much and for how long are decided by your surgeon.
Before you go home, most teams want to see stable vital signs, pain controlled on oral medicine, the ability to urinate, a dry or minimally draining dressing, and safe walking and stair work with a walker or crutches as judged by physical therapy. You may go home the same day or stay in the hospital for 1 to 2 days while recovering from anesthesia and surgery (MedlinePlus); the AAOS figure reported by Medical News Today is a stay of 1 to 4 days.
If you had general anesthesia or moderate (conscious) sedation, you cannot drive yourself home. A responsible adult must drive you, and most facilities also require someone to stay with you for the first 24 hours after discharge. Line that person up at least 24 hours before your surgery date — surgery is commonly cancelled when no driver is available. Confirm your own hospital's exact discharge and escort rules with your care team, because they differ by facility.

